While akinesia is the most disabling of the three
primary manifestations of Parkinson's disease
, it is poorly defined [12].
Taber's Cyclopedic Medical Dictionary defines it simply as ``complete
or partial loss of muscle movement'' [78]. Other authors
present similar definitions
[32,63,42].
Delwaide and Gonce [12] and Imai et al.\ [31] provide more detailed lists of possible symptoms of akinesia: see Appendix C.
For the purposes of this thesis, the generic definition of akinesia as ``difficulty initiating and maintaining motion'' is sufficient.